| Description | AZD4619 is a potent, selective and reversible orally bioavailable agonist of PPARα receptor. |
| Synonyms | AZ11942571, AZD-4619, AZD 4619 |
| molecular weight | 518.6 |
| Molecular formula | C25H26O8S2 |
| CAS | 1067247-60-2 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Thulin P, Bamberg K, Buler M, Dahl B, Glinghammar B. The peroxisome proliferator-activated receptor α agonist, AZD4619, induces alanine aminotransferase-1 gene and protein expression in human, but not in rat hepatocytes: Correlation with serum ALT levels. Int J Mol Med. 2016 Sep;38(3):961-8. doi: 10.3892/ijmm.2016.2681. PubMed PMID: 27430334. 2. Thulin P, Rafter I, Stockling K, Tomkiewicz C, Norjavaara E, Aggerbeck M, Hellmold H, Ehrenborg E, Andersson U, Cotgreave I, Glinghammar B. PPARalpha regulates the hepatotoxic biomarker alanine aminotransferase (ALT1) gene expression in human hepatocytes. Toxicol Appl Pharmacol. 2008 Aug 15;231(1):1-9. doi: 10.1016/j.taap.2008.03.007. PubMed PMID: 18455211. |