| Description | AVP-13358 is a CD23 antagonist (immunoglobulin ε-Fc receptor antagonist), an immunoglobulin E inhibitor. AVP-13358 has potent activity against IgE, cytokines and CD23 and is used in the treatment of immune system disorders, infections and otolaryngological disorders. |
| molecular weight | 491.58 |
| Molecular formula | C30H29N5O2 |
| CAS | 459805-03-9 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 1 mg/mL, Sonication is recommended. |
| References | 1. Richards ML, et al. Novel 2-(substituted phenyl)benzimidazole derivatives with potent activity against IgE, cytokines, and CD23 for the treatment of allergy and asthma. J Med Chem. 2004;47(26):6451-6454. 2. Banie H, et al. 2-phenylimidazopyridines, a new series of Golgi compounds with potent antiviral activity. J Med Chem. 2007;50(24):5984-5993. |