| Description | ATX inhibitor 15 (compound 30) is an indole-based carbamate derivative with a strong inhibitory effect on autotaxin (ATX), demonstrated by an IC50 of 2.17 nM. Additionally, ATX inhibitor 15 effectively inhibits ATX activity in vivo and suppresses the expression of pro-fibrotic genes. Furthermore, ATX inhibitor 15 exhibits protective effects in lung fibrosis induced by Bleomycin in mice [1]. |
| molecular weight | 558.09 |
| Molecular formula | C27H32ClN5O4S |
| CAS | 2484811-52-9 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |