| Description | ATPA is a selective glutamate receptor GluR5 activator (EC50s: 0.66, 1.4, 9.5, 23, 32, 18, and 14 μM for GluR5wt, GluR5(S721T), GluR5(S741M), GluR5(S721T, S741M), GluR5(S741A), GluR5(S741L), and GluR5(S741V)). |
| In vitro | ATPA also activates GluR1wt, GluR1(M722S), GluR1(T700S), GluR1(T700S, M722S), GluR1(M722A) (EC50s: 62, 4.6, 97, 14, 97 μM). |
| molecular weight | 228.24 |
| Molecular formula | C10H16N2O4 |
| CAS | 140158-50-5 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| References | 1. Nielsen MM, et al. The selective activation of the glutamate receptor GluR5 by ATPA is controlled by serine 741. Mol Pharmacol. 2003 Jan;63(1):19-25. |