| Description | ATIC-IN-1 (compound 14) acetate is an ATIC dimerization inhibitor with a K i value of 685 nM, essential for AICAR transformylase activity. It demonstrates anti-tumor effects by decreasing cell proliferation and division rates [1]. |
| In vitro | ATIC-IN-1醋酸盐（10 μM、50 μM）是一种特异性抑制剂，无论BSA浓度是1 mg/mL或10 mg/mL，均显示出非特异性的聚集现象[1]。ATIC-IN-1醋酸盐（100-500 μM；48小时）能抑制MCF-7细胞增殖[1]。ATIC-IN-1醋酸盐（250 μM；24-72小时）作用于分裂而非促使细胞死亡增加[1]。 |
| molecular weight | 523.58 |
| Molecular formula | C23H37N7O7 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |