| Description | Astrophloxine is a fluorescent imaging probe capable of targeting antiparallel dimers.Astrophloxine can be used to detect aggregated Aβ in brain tissue and cerebrospinal fluid samples from Alzheimer's disease (AD) mice. |
| molecular weight | 512.47 |
| Molecular formula | C27H33IN2 |
| CAS | 14696-39-0 |
| Storage | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 55 mg/mL (107.32 mM) |
| References | 1. Lee JC, et al. Discovery of Chemicals to Either Clear or Indicate Amyloid Aggregates by Targeting Memory-Impairing Anti-Parallel Aβ Dimers. Angew Chem Int Ed Engl. 2020 Jul 6;59(28):11491-11500. |