| Description | ASO 556089, a 16-nucleotide antisense oligonucleotide (3-10-3 gap protein), targets the long non-coding RNA MALAT1 in both humans and mice. It has the sequence 5'-GmCATTmCTAATAGmCAGmC-3' [1]. |
| In vitro | ASO 556089（0.16-40 µM；72小时）针对2D HRPTEC培养中的PCSK9和MALAT1进行靶向作用[1]。ASO 556089（1和10µM；48小时）在芯片上培养的HRTEC中引起目标转录下调[1]。ASO 556089（0.31-5 µM；48小时）抑制2D HRPTEC培养中的MALAT1基因表达[1]。ASO 556089（40 µM；72小时）未引起细胞毒性[1]。 |
| molecular weight | N/A |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |