| Description | AS1928370 is an antagonist of transient receptor potential vanilloid 1 (TRPV1). |
| molecular weight | 453.58 |
| Molecular formula | C29H31N3O2 |
| CAS | 1345614-89-2 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Watabiki T, Kiso T, Tsukamoto M, Aoki T, Matsuoka N. Intrathecal administration of AS1928370, a transient receptor potential vanilloid 1 antagonist, attenuates mechanical allodynia in a mouse model of neuropathic pain. Biol Pharm Bull. 2011;34(7):1105-8. PubMed PMID: 21720020. 2. Watabiki T, Kiso T, Kuramochi T, Yonezawa K, Tsuji N, Kohara A, Kakimoto S, Aoki T, Matsuoka N. Amelioration of neuropathic pain by novel transient receptor potential vanilloid 1 antagonist AS1928370 in rats without hyperthermic effect. J Pharmacol Exp Ther. 2011 Mar;336(3):743-50. doi: 10.1124/jpet.110.175570. Epub 2010 Nov 22. PubMed PMID: 21098091. |