| Description | Arundic Acid (ONO 2506) is an astrocyte-modulating agent, delays the expansion of cerebral infarcts by modulating the activation of astrocytes through inhibition of S-100β synthesis. |
| Synonyms | ONO 2506, (R)-2-丙基辛酸, (R)-2-Propyloctanoic acid |
| molecular weight | 186.29 |
| Molecular formula | C11H22O2 |
| CAS | 185517-21-9 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 150 mg/mL (805.20 mM), Sonication is recommended. |
| References | 1. Tomoyuki Hasegawa, et al. Process Development of ONO-2506: A Therapeutic Agent for Stroke and Alzheimer's Disease. Org. Process Res. Dev.200372168-171. 2. Kato H, et al. Arundic acid, an astrocyte-modulating agent, protects dopaminergic neurons against MPTPneurotoxicity in mice. Brain Res. 2004 Dec 24;1030(1):66-73. |