| Description | ARC 239 dihydrochloride is a selective α2B adrenoceptor antagonist (pKD values are 8.8, 6.7 and 6.4 at α2B, α2A, and α2D receptors respectively). |
| molecular weight | 480.43 |
| Molecular formula | C24H31Cl2N3O3 |
| CAS | 55974-42-0 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 50 mg/mL (104.07 mM) |
| References | 1. Suzana Assad Kahn, et al. The anti-hypertensive drug prazosin inhibits glioblastoma growth via the PKCδ-dependent inhibition of the AKT pathway. EMBO Mol Med. 2016 May 2;8(5):511-26. |