| Description | AQC (6-Aminoquinolyl-N-hydroxysccinimidyl carbamate) (6-Aminoquinolyl-N-hydroxysccinimidyl carbamate) is a reagent for the fluorescence detection of amino acid or protein sequence by HPLC. AQC reacts with primary and secondary amino acids to produce fluorescent derivatives, allowing the detection of amino acids at picomolar levels. |
| Synonyms | 6-Aminoquinolyl-N-hydroxysccinimidyl carbamate |
| molecular weight | 285.25 |
| Molecular formula | C14H11N3O4 |
| CAS | 148757-94-2 |
| Storage | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 95 mg/mL (333.04 mM), Sonication is recommended. |
| References | 1. Application of the 6-aminoquinolyl-N-hydroxysccinimidyl carbamate (AQC) reagent to the RP-HPLC determination of amino acids in infant foods[J]. Journal of Chromatography B Analytical Technologies in the Biomedical & Life Sciences, 2006, 831(1-2):176-183. 2. Applications of amino acid derivatization with 6-aminoquinolyl-N-hydroxysuccinimidyl carbamate. Analysis of feed grains, intravenous solutions and glycoproteins.[J]. Journal of Chromatography A, 1994, 661(1-2):25-34. |
| Citations | 1. Yu Z, Li H, Jia Y Y, et al. Ratiometric co-delivery of doxorubicin and docetaxel by covalently conjugating with mPEG-poly (β-malic acid) for enhanced synergistic breast tumor therapy. Polymer Chemistry. 2020, 11(46): 7330-7339 |