| Description | Aptiganel (CNS-1102) is a non-competitive NMDA antagonist, a peptide that may be used to study acute ischemic stroke. |
| Synonyms | CNS 1102, CNS-1102, CNS1102 |
| molecular weight | 303.4 |
| Molecular formula | C20H21N3 |
| CAS | 137159-92-3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| References | 1. Kroppenstedt SN, et al. Neuroprotective properties of aptiganel HCL (Cerestat) following controlled cortical impact injury. Acta Neurochir Suppl. 1998;71:114-116. 2. McBurney RN. Development of the NMDA ion-channel blocker, aptiganel hydrochloride, as a neuroprotective agent for acute CNS injury. Int Rev Neurobiol. 1997;40:173-195. 3. Kroppenstedt SN,et al. Protective effects of aptiganel HCl (Cerestat) following controlled cortical impact injury in the rat. J Neurotrauma. 1998 Mar;15(3):191-7. 4. Bokesch PM, et al. Immediate-early gene expression in ovine brain after hypothermic circulatory arrest: effects of aptiganel. Ann Thorac Surg. 1997 Oct;64(4):1082-7; discussion 1088. |