| Description | AP1867-2-(carboxymethoxy), a moiety based on the synthetic FKBP12F36V-directed ligand AP1867, connects to the CRBN ligand through a linker to generate dTAG molecules[1]. |
| In vitro | dTAG molecules engage FKBP12F36V and CRBN[1]. |
| Synonyms | PROTAC FKBP12-binding moiety 2 |
| molecular weight | 693.78 |
| Molecular formula | C38H47NO11 |
| CAS | 2230613-03-1 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| References | 1. Nabet B, et al. The dTAG system for immediate and target-specific protein degradation. Nat Chem Biol. 2018 May;14(5):431-441. |