| Description | Antimycobacterial agent-6 (compound 25) effectively inhibits Mycobacterium tuberculosis, including wild-type and fluoroquinolone-resistant strains, by targeting the Mtb DprE1-C387S mutant. It displays minimal inhibitory concentrations (MIC90) of 0.9 μM for H37Rv and MoxR strains, and 0.5 μM for the DprE1-P116S strain [1]. |
| molecular weight | 475.34 |
| Molecular formula | C20H15F6N3O4 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |