| Description | Antifungal agent 68 (compound 10) effectively combats fungal infections caused by Candida and Cryptococcus gattii through the inhibition of ergosterol biosynthesis, likely via interaction with lanosterol 14α-demethylase (CYP51). It is proposed that the imidazole ring of antifungal agent 68 interacts with the heme group of CYP51 [1]. |
| molecular weight | 414.93 |
| Molecular formula | C23H27ClN2O3 |
| CAS | 2925307-53-3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |