| Description | Anti-TNBC agent-3 (compound 3g) is a compound that induces apoptosis and possesses anti-cancer cell proliferation properties. It effectively inhibits tumor growth and metastasis in xenograft models of triple-negative breast cancer (TNBC) [1]. |
| In vitro | 抗TNBC药物-3（化合物3g）对K562及HepG2细胞增殖的半抑制浓度（IC50）分别为0.24μM与0.25μM[1]。 |
| In vivo | 抗TNBC药物-3（化合物3g）（剂量分别为10 mg/kg和20 mg/kg；腹腔注射）有效抑制了小鼠三阴性乳腺癌异种移植肿瘤模型中的肿瘤生长及其转移[1]。 |
| molecular weight | 539.66 |
| Molecular formula | C29H39F2N7O |
| CAS | 2422001-25-8 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |