| Description | Anti-osteoporosis agent-1 (comp 4aa) is an effective RPA (replication protein A) inhibitor, demonstrating potency with an IC50 value of 18 μM [1]. |
| In vitro | Anti-osteoporosis agent-1 is an active molecule which showed effective mineralisation of osteoblast cells and up regulates the osteogenic marker gene such as Bmp-2, Runx-2 and Type-1col at both transcriptional and translational level. Besides exhibiting potential osteogenic activity. In addition, Anti-osteoporosis agent-1 also own significant anti-apoptotic activity at 1 pM &100 pM concentration and increases the osteoblast survival in serum deprived conditions [1]. |
| molecular weight | 354.83 |
| Molecular formula | C20H19ClN2O2 |
| CAS | 2761577-50-6 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |