Description | Anti-Influenza agent 4 is a potent and selective inhibitor of influenza virus, inhibiting A/Parma and A/Roma strains with EC50s of 62 nM and 150 nM, respectively. |
In vitro | Anti influenza agent 4(0-500 μM;24小时和48小时)在Madin-Darby犬肾细胞中展现了低细胞毒性。[1] 在溶血抑制实验中,Anti influenza agent 4 对流感毒株A/Roma和A/Parma的IC50分别为244 nM和230.7 nM。[1] |
Target activity | A/Roma:62±0.02 nM, A/Roma:150±0.07 nM |
molecular weight | 386.42 |
Molecular formula | C19H18N2O5S |
CAS | 522625-85-0 |
Storage | |Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
Solubility | DMSO: 45 mg/mL (116.45 mM) |
References | 1. Agamennone M, et al. Identification of small molecules acting against H1N1 influenza A virus. Virology. 2016;488:249-258. |