| Description | Angelic anhydride ((Z)-2-Methylbut-2-enoic anhydride) is a reagent in the improved synthesis of angelate esters, which are the active chemical behind the strong pain-relieving and spasmolytic action of extracts from the plant butterbur. |
| Synonyms | 2-Methylisocrotonic Anhydride, 当归酸酐, (Z)-2-Methylbut-2-enoic anhydride |
| molecular weight | 182.22 |
| Molecular formula | C10H14O3 |
| CAS | 94487-74-8 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.: Soluble DMSO: 70 mg/mL (384.17 mM) |
| References | 1. Sonobe, H., et al.: J. Agricul. Food Chem., 29 (6), 1125 (1981); 2. Liang, X., Grue-Sørensen, G., Petersen, A., & Högberg, T. (2012). Semisynthesis of Ingenol 3-Angelate (PEP2005): Efficient Stereoconservative Angeloylation of Alcohols. Synlett, 23(18), 2647-2652. doi: 10.1055/s-20032-1317415 |