| Description | Anemonin is a natural product from Pulsatilla chinensis Regel. |
| In vitro | 当人类关节软骨细胞和软骨组织块面临白细胞介素-1β（IL-1β）的挑战时，采用了Anemonin进行处理。Anemonin能够减缓因IL-1β处理而导致的人类软骨组织块中蛋白多糖的丧失，并在体外实验中延缓关节软骨的退化进程[1]。 |
| In vivo | 在10周龄的雄性C57BL/6J小鼠中进行了内侧半月板松动（DMM）操作。随后，Anemonin被关节腔内注射至关节囊中，注射周期分别为8周和12周。研究发现，Anemonin能够延缓关节软骨退化的in vivo过程。此外，Anemonin降低了... |
| molecular weight | 192.17 |
| Molecular formula | C10H8O4 |
| CAS | 90921-11-2 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Wang Z , Huang J , Zhou S , et al. Anemonin attenuates osteoarthritis progression through inhibiting the activation of IL-1β/NF-κB pathway[J]. Journal of Cellular and Molecular Medicine, 2017. |