| Description | Amifostine sodium is a phosphorothioate proposed as a radiation-protective agent. It causes splenic vasodilation and may block autonomic ganglia. |
| Synonyms | WR-2721 sodium, WR2721 sodium, WR 2721 sodium |
| molecular weight | 237.21 |
| Molecular formula | C5H15N2NaO3PS |
| CAS | 59178-37-9 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Jaćević V, Dragojević-Simić V, Tatomirović Ž, Dobrić S, Bokonjić D, Kovačević A, Nepovimova E, Vališ M, Kuča K. The Efficacy of Amifostine against Multiple-Dose Doxorubicin-Induced Toxicity in Rats. Int J Mol Sci. 2018 Aug 12;19(8). pii: E2370. doi: 10.3390/ijms19082370. PubMed PMID: 30103540. 2. Sueishi Y, Nii R. Monoterpene's multiple free radical scavenging capacity as compared with the radioprotective agent cysteamine and amifostine. Bioorg Med Chem Lett. 2018 Aug 2. pii: S0960-894X(18)30652-8. doi: 10.1016/j.bmcl.2018.08.003. [Epub ahead of print] PubMed PMID: 30098868. |