| Description | Ambruticin is a biochemical. |
| Synonyms | W7783, W 7783, W-7783 |
| molecular weight | 474.63 |
| Molecular formula | C28H42O6 |
| CAS | 58857-02-6 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Hemmerling F, Lebe KE, Wunderlich J, Hahn F. An Unusual Fatty Acyl:Adenylate Ligase (FAAL)-Acyl Carrier Protein (ACP) Didomain in Ambruticin Biosynthesis. Chembiochem. 2018 Mar 8. doi: 10.1002/cbic.201800084. [Epub ahead of print] PubMed PMID: 29517170. 2. Ma Y, Yun YK, Wondergem Nee Lukesh J, Sar A, Gone JR, Lindeman S, Donaldson WA. Reactivity of (1-methoxycarbonylpentadienyl)iron(1+) cations with hydride, methyl, and nitrogen nucleophiles. Tetrahedron. 2017 Jul 27;73(30):4493-4500. doi: 10.1016/j.tet.2017.06.026. Epub 2017 Jun 15. PubMed PMID: 29200513; PubMed Central PMCID: PMC5703425. 3. Sung KH, Berkhan G, Hollmann T, Wagner L, Blankenfeldt W, Hahn F. Insights into the Dual Activity of a Bifunctional Dehydratase-Cyclase Domain. Angew Chem Int Ed Engl. 2018 Jan 2;57(1):343-347. doi: 10.1002/anie.201707774. Epub 2017 Dec 6. PubMed PMID: 29084363. 4. Berkhan G, Merten C, Holec C, Hahn F. The Interplay between a Multifunctional Dehydratase Domain and a C-Methyltransferase Effects Olefin Shift in Ambruticin Biosynthesis. Angew Chem Int Ed Engl. 2016 Oct 17;55(43):13589-13592. doi: 10.1002/anie.201607827. Epub 2016 Sep 27. PubMed PMID: 27670141. |