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Amastatin hydrochloride

CAS No.: 100938-10-1

Amastatin HCl is an inhibitor of aminopeptidase. It also induces vasoconstriction.
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Description Amastatin HCl is an inhibitor of aminopeptidase. It also induces vasoconstriction.
Synonyms 氨肽酶抑制剂盐酸盐, BIMI-1803, Amastatin HCl, ZX-AFC000547, ZXAFC000547, BIMI1803, J-000280, J000280
molecular weight 511.01
Molecular formula C21H39ClN4O8
CAS 100938-10-1
Storage Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility DMSO: Soluble
References 1. Kawabata A, Kinoshita M, Nishikawa H, Kuroda R, Nishida M, Araki H, Arizono N, Oda Y, Kakehi K. The protease-activated receptor-2 agonist induces gastric mucus secretion and mucosal cytoprotection. J Clin Invest. 2001 Jun;107(11):1443-50. PubMed PMID: 11390426; PubMed Central PMCID: PMC209315. 2. Kawabata A, Oono Y, Yonezawa D, Hiramatsu K, Inoi N, Sekiguchi F, Honjo M, Hirofuchi M, Kanke T, Ishiwata H. 2-Furoyl-LIGRL-NH2, a potent agonist for proteinase-activated receptor-2, as a gastric mucosal cytoprotective agent in mice. Br J Pharmacol. 2005 Jan;144(2):212-9. PubMed PMID: 15655521; PubMed Central PMCID: PMC1575994. 3. Gee NS, Kenny AJ. Proteins of the kidney microvillar membrane. Enzymic and molecular properties of aminopeptidase W. Biochem J. 1987 Aug 15;246(1):97-102. PubMed PMID: 2890346; PubMed Central PMCID: PMC1148244. 4. Kawabata A, Nishikawa H, Saitoh H, Nakaya Y, Hiramatsu K, Kubo S, Nishida M, Kawao N, Kuroda R, Sekiguchi F, Kinoshita M, Kakehi K, Arizono N, Yamagishi H, Kawai K. A protective role of protease-activated receptor 1 in rat gastric mucosa. Gastroenterology. 2004 Jan;126(1):208-19. PubMed PMID: 14699501.