PeptideDB

AM-156

CAS No.: 1224977-85-8

AM-156 is a bio-active chemical.
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This product is for research use only, not for human use. We do not sell to patients.

Description AM-156 is a bio-active chemical.
Synonyms AM 156, UNII-5V9HJQ1Y75
molecular weight 458.433
Molecular formula C23H24F3NNaO4
CAS 1224977-85-8
Storage Powder: -20°C for 3 years | In solvent: -80°C for 1 year
References 1. Stebbins KJ, Broadhead AR, Musiyenko A, Barik S, Scott JM, Truong YP, Stearns BA, Hutchinson JH, Prasit P, Evans JF, Lorrain DS. DP2 (CRTh2) antagonism reduces ocular inflammation induced by allergen challenge and respiratory syncytial virus. Int Arch Allergy Immunol. 2012;157(3):259-68. doi: 10.1159/000328769. Epub 2011 Oct 28. PubMed PMID: 22042170. 2. Stebbins KJ, Broadhead AR, Correa LD, Scott JM, Truong YP, Stearns BA, Hutchinson JH, Prasit P, Evans JF, Lorrain DS. Therapeutic efficacy of AM156, a novel prostanoid DP2 receptor antagonist, in murine models of allergic rhinitis and house dust mite-induced pulmonary inflammation. Eur J Pharmacol. 2010 Jul 25;638(1-3):142-9. doi: 10.1016/j.ejphar.2010.04.031. Epub 2010 May 4. PubMed PMID: 20447387. 3. Stebbins KJ, Broadhead AR, Baccei CS, Scott JM, Truong YP, Coate H, Stock NS, Santini AM, Fagan P, Prodanovich P, Bain G, Stearns BA, King CD, Hutchinson JH, Prasit P, Evans JF, Lorrain DS. Pharmacological blockade of the DP2 receptor inhibits cigarette smoke-induced inflammation, mucus cell metaplasia, and epithelial hyperplasia in the mouse lung. J Pharmacol Exp Ther. 2010 Mar;332(3):764-75. doi: 10.1124/jpet.109.161919. Epub 2009 Dec 8. PubMed PMID: 19996299.