| Description | Alvelestat can inhibit neutrophil elastase (NE), which acts an important role in NET formation. |
| Target activity | Neutrophil elastase:Kd: 9.5 nM |
| molecular weight | 717.73 |
| Molecular formula | C32H30F3N5O7S2 |
| CAS | 1240425-05-1 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Li H, Zhou X, Tan H, Hu Y, Zhang L, Liu S, Dai M, Li Y, Li Q, Mao Z, Pan P, Su X, Hu C. Neutrophil extracellular traps contribute to the pathogenesis of acid-aspiration-induced ALI/ARDS. Oncotarget. 2017 Nov 28;9(2):1772-1784. doi: 10.18632/oncotarget.22744. eCollection 2018 Jan 5. PubMed PMID: 29416730; PubMed Central PMCID: PMC5788598. |