| Description | Aluminum Hydroxide is an orally active main form of aluminum used as an adjuvant. Aluminum hydroxide-based adjuvant researches including the repository effect, pro-phagocytic effect, and activation of the pro-inflammatory NLRP3 pathway. |
| In vivo | Aluminum Hydroxide (orally; 100 mg/kg/day for 7 days) increases lipid peroxidation and decreases the activity of SOD in the brain. It can dissolve in distilled water to be a homogeneous suspension [3]. |
| molecular weight | 78 |
| Molecular formula | AlH3O3 |
| CAS | 21645-51-2 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 1 mg/mL (12.82 mM), Sonication is recommended. |
| References | 1. He P, et al. Advances in aluminum hydroxide-based adjuvant research and its mechanism. Hum Vaccin Immunother. 2015;11(2):477-88. 2. Amini Y, et al. Aluminum hydroxide nanoparticles show strong activity to stimulate Th-1 immune response against tuberculosis. Artif Cells Nanomed Biotechnol. 2017 Nov;45(7):1331-1335. 3. Ohtawa M, et al. Effect of aluminum ingestion on lipid peroxidation in rats. Chem Pharm Bull (Tokyo). 1983 Apr;31(4):1415-8. |