| Description | Alrestatin is a specific inhibitor of the aldose reductase enzyme. |
| Synonyms | AY 22284A, AY-22284A, Alrestatine sodium, AY22284A |
| molecular weight | 278.219 |
| Molecular formula | C14H9NNaO4 |
| CAS | 51876-97-2 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Lippmann W, Seethaler K, Borella LE, Pugsley TA. Alrestatin: gastric acid antisecretory-antiulcer activity in the rat. Digestion. 1978;18(1-2):35-44. PubMed PMID: 103765. 2. Kobric M, Lippmann W. Effect of alrestatin sodium on glucose-stimulated insulin secretion in the fasted anaesthetized rat. Horm Metab Res. 1978 Nov;10(6):495-500. PubMed PMID: 744568. 3. Srivastava SK, Ansari NH, Bhatnagar A, Hair G, Liu S, Das B. Activation of aldose reductase by nonenzymatic glycosylation. Prog Clin Biol Res. 1989;304:171-84. PubMed PMID: 2506561. 4. Brogard JM, Caro-Sampara F, Blicklé JF. [Role of polyols in the development of diabetic complications. Value of aldose-reductase inhibitors]. Rev Med Interne. 1992 Jan-Feb;13(1):69-79. Review. French. PubMed PMID: 1410879. |