Description | α-hydroxy Farnesyl phosphonic acid is a nonhydrolyzable analog of farnesyl pyrophosphate which acts as a competitive inhibitor of farnesyl transferase (FTase). At concentrations greater than 1 μM, α-hydroxy farnesyl phosphonic acid inhibits the processing of Ras in Ha-ras-transformed NIH3T3 cells. |
molecular weight | 302.35 |
Molecular formula | C15H27O4P |
CAS | 148796-53-6 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
Solubility | PBS (pH 7.2): <25 μg/mL Ethanol: >25 mg/mL 10 mM Na2CO3: Freely Soluble |