Description | α-HNJNAc is a potent, competitive hexosaminidases inhibitor that does not interfer with other glycosidases [1]. |
In vitro | α-HNJNAc (10, 100μM) has no effect on GM00737 and GM01426 cell lines, but has some effect on GM02931 cell line with a significant 1.8 fold activity increase. a-HNJNAc (100μM; 3 days) has no toxicity on human HL60 cell proliferation [1]. NAGLU is inhibited more efficiently by a-HNJNAc (67 μM) than by the uncorrectly configured b-HNJNAc (374 μM) [1]. |
molecular weight | 234.25 |
Molecular formula | C9H18N2O5 |
CAS | 1417906-42-3 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |