| Description | Almorexant (ACT 078573) is a potent and competitive dual orexin 1 receptor (OX1)/orexin 2 receptor (OX2) antagonist with Ki values of 1.3 and 0.17 nM for OX1 and OX2, respectively. |
| Target activity | OX2:0.17 nM(ki), OX1:1.3 nM(ki) |
| Synonyms | 阿莫伦特, ACT 078573 |
| molecular weight | 512.56 |
| Molecular formula | C29H31F3N2O3 |
| CAS | 871224-64-5 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 45 mg/mL (87.79 mM) |
| References | 1. Malherbe P, et al. Mol Pharmacol. 2009 Sep;76(3):618-31. |