| Description | ALK-IN-23 is a potent inhibitor of ALK, acting on ALKWT (IC50: 1.6 nM), ALKL1196M (IC50: 0.71 nM) and ALKG1202R (IC50: 1.3 nM). -IN-23 has inhibitory effects on cancer cell migration and colony formation in vitro. In the H2228 xenograft nude mouse model, ALK-IN-23 showed good anti-tumour effects with low toxicity. |
| molecular weight | 569.08 |
| Molecular formula | C26H29ClN8O3S |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |