| Description | AFK-108 is a fungicide agent. |
| molecular weight | 393.35 |
| Molecular formula | C21H26Cl2N2O |
| CAS | 135330-85-7 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Hori K, Sakaguchi A, Kudoh M, Ishida K, Aoyama Y, Yoshida Y. Structure-activity relationships of a new antifungal imidazole, AFK-108, and related compounds. Chem Pharm Bull (Tokyo). 2000 Jan;48(1):60-4. PubMed PMID: 10705477. 2. Ito T, Aoyama Y, Ishida K, Kudoh M, Hori K, Tsuchiya S, Yoshida Y. Selectivity of isoprenoid-containing imidazole antifungal compounds for sterol 14-demethylase P450 (P450(14)DM) and 7-ethoxycoumarin O-deethylase P450 of rat liver microsomes. Biochem Pharmacol. 1994 Oct 18;48(8):1577-82. PubMed PMID: 7980623. 3. Aoyama Y, Ishida K, Hori K, Sakaguchi A, Kudoh M, Yoshida Y. Inhibition by a novel azole antifungal agent with a geranyl group on lanosterol 14 alpha-demethylase of yeast. Biochem Pharmacol. 1992 Nov 3;44(9):1701-5. PubMed PMID: 1449529. |