| Description | Adrenocorticotropic Hormone (ACTH) (4-10), human is an agonist of potent melanocortin(MC4R) receptor . |
| In vivo | 在人体中，Adrenocorticotropic Hormone (ACTH) (4-10) 经由鼻腔给药后会进入脑脊液区域，并在持续治疗6周后导致身体总脂肪量下降[1]。 |
| Synonyms | Adrenocorticotropic Hormone (ACTH) (4-10), ACTH (4-10), human, Acth (4-10) |
| molecular weight | 962.09 |
| Molecular formula | C44H59N13O10S |
| CAS | 4037-01-8 |
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 10 mM |
| References | 1. Wellhöner P, et al. Intranasal application of the melanocortin 4 receptor agonist MSH/ACTH(4-10) in humans causes lipolysis in white adipose tissue. Int J Obes (Lond). 2012 May;36(5):703-8. 2. Krude H , Biebermann H , Schnabel D , et al. Obesity Due to Proopiomelanocortin Deficiency: Three New Cases and Treatment Trials with Thyroid Hormone and ACTH4–10[J]. The Journal of Clinical Endocrinology & Metabolism, 2003, 88(10):4633-4640. |