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ACTH 4-11 acetate

CAS No.:

ACTH 4-11 acetate is an adrenocorticotropin hormone fragment and possesses the same amino acid sequence as α-melanocyte
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Description ACTH 4-11 acetate is an adrenocorticotropin hormone fragment and possesses the same amino acid sequence as α-melanocyte stimulating hormone (MSH) does. ACTH 4-11 acetate exhibits a weak MSH potency only at high doses (100 and 1000 nM).
In vitro MSH能够促进小鼠表皮黑色素细胞在体内外的分化,而ACTH 4-11 acetate几乎失去了与黑色素皮质素受体1(MC1R)[1]结合的活性。
Synonyms ACTH 4-11 acetate (67224-41-3 Free base)
molecular weight 1150.31
Molecular formula C52H75N15O13S
Storage keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
References 1. Hirobe T, et al. ACTH(4-12) is the minimal message sequence required to induce the differentiation of mouse epidermal melanocytes in serum-free primary culture. J Exp Zool. 2000 May 1;286(6):632-40.