| Description | ACTH 4-11 acetate is an adrenocorticotropin hormone fragment and possesses the same amino acid sequence as α-melanocyte stimulating hormone (MSH) does. ACTH 4-11 acetate exhibits a weak MSH potency only at high doses (100 and 1000 nM). |
| In vitro | MSH能够促进小鼠表皮黑色素细胞在体内外的分化,而ACTH 4-11 acetate几乎失去了与黑色素皮质素受体1(MC1R)[1]结合的活性。 |
| Synonyms | ACTH 4-11 acetate (67224-41-3 Free base) |
| molecular weight | 1150.31 |
| Molecular formula | C52H75N15O13S |
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| References | 1. Hirobe T, et al. ACTH(4-12) is the minimal message sequence required to induce the differentiation of mouse epidermal melanocytes in serum-free primary culture. J Exp Zool. 2000 May 1;286(6):632-40. |