| Description | Acridine Orange hydrochloride is a fluorescent dye of cell-permeable. It binds to nucleic acids, resulting in an altered spectral emission.It is used as a supravital stain and in fluorescence cytochemistry. It may cause mutations in microorganisms. |
| Synonyms | 吖啶橙, 3,6-双(二甲基氨基)吖啶 |
| molecular weight | 301.81 |
| Molecular formula | C17H20ClN3 |
| CAS | 65-61-2 |
| Storage | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 3.02 mg/mL (10 mM), Sonication is recommended. H2O: 50 mg/mL (165.67 mM), Sonication and heating are recommended. |
| References | 1. McMaster GK, et al. Analysis of single- and double-stranded nucleic acids on polyacrylamide and agarosegels by using glyoxal and acridine orange. Proc Natl Acad Sci U S A. 1977 Nov;74(11):4835-8. 2. Traganos F, et al. Simultaneous staining of ribonucleic and deoxyribonucleic acids in unfixed cells using acridine orange in a flow cytofluorometric system. J Histochem Cytochem. 1977 Jan;25(1):46-56. |
| Citations | 1. Wu Q, Song M, Luo S, et al.Unveil the mechanism for EHMT--A novel triterpenoid inhibits proliferation and induces apoptosis in colon cancer through ROS-mediated JNK signaling pathway.Biomedicine & Pharmacotherapy.2024, 174: 116469. |