| Description | Acid-PEG4-S-S-PEG4-acid is a polyethylene glycol (PEG)-based PROTAC linker, which serves as a key component in the synthesis of PROTACs. |
| In vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| molecular weight | 562.69 |
| Molecular formula | C22H42O12S2 |
| CAS | 2055015-40-0 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| References | 1. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |