| Description | ACHE Inhibitor 12 inhibited acetylcholinesterase with an IC50 value of 0.38 µM. |
| Target activity | AChE:0.38 µM |
| molecular weight | 160.21 |
| Molecular formula | C11H12O |
| CAS | 66309-83-9 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 18.33 mg/mL (114.43 mM), Sonication is recommended. |
| References | 1. Pinnick H W, et al. Friedel-Crafts reactions of ethyl cyclopropanecarboxylate. The Journal of Organic Chemistry, 1981, 46(18): 3758-3760. 2. Cardozo MG, et al. QSAR analyses of the substituted indanone and benzylpiperidine rings of a series of indanone-benzylpiperidine inhibitors of acetylcholinesterase [published correction appears in J Med Chem 1992 Dec 11;35(25):4767]. J Med Chem. 1992;35(3):584-589. |