Description | AChE-IN-11 (compound 5C) can be used in the Alzheimer's disease research with neuroprotective effects and good antioxidant activity (ORAC = 2.5 eq). AChE-IN-11 is a good multifunctional agent with IC 50 values of 7.9 μM, 9.9 μM, and 8.3 μM against AChE, MAO-B, and BACE1. AChE-IN-11 has a mixed-type AChE inhibition that can bind to the CAS and PAS of AChE. AChE-IN-11 is also a selective metal ions chelator [1]. |
molecular weight | 336.43 |
Molecular formula | C18H28N2O4 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |