| Description | ACG416B (compound 18) exhibits formidable inhibitory effects on choline kinase (ChoK), with an IC 50 measurement of 0.4 μM. Notably, ACG416B demonstrates superior inhibitory activities against HT-29 human colon cancer cells, resulting in pronounced antiproliferative effects. |
| molecular weight | 708.542 |
| Molecular formula | C38H36Br2N4 |
| CAS | 795316-15-3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. onejo-García A, et al. Influence of the linker in bispyridium compounds on the inhibition of human choline kinase. J Med Chem. 2004 Oct 21;47(22):5433-40. |