| Description | ABCG2-IN-1 (compound K2), an analog of Ko143, constitutes an orally active inhibitor targeting ABCG2 with an inhibitory concentration (IC50) of 0.13 μM. Demonstrating favorable oral pharmacokinetics in mice, ABCG2-IN-1 showcases promise for further research [1]. |
| molecular weight | 468.59 |
| Molecular formula | C26H36N4O4 |
| CAS | 2559759-40-7 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |