| Description | Abafungin (Bay w 6341) is an antifungal agent with a broad-spectrum. |
| Synonyms | 阿巴芬净, Bay w 6341, UNII-11DI31LWXF |
| molecular weight | 378.49 |
| Molecular formula | C21H22N4OS |
| CAS | 129639-79-8 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 3.79 mg/mL (10 mM) H2O: Insoluble |
| References | 1. Rouf A, Tanyeli C. Bioactive thiazole and benzothiazole derivatives. Eur J Med Chem. 2015 Jun 5;97:911-27. doi: 10.1016/j.ejmech.2014.10.058. Epub 2014 Oct 22. Review. PubMed PMID: 25455640. 2. Tomillero A, Moral MA. Gateways to clinical trials. Methods Find Exp Clin Pharmacol. 2010 Jan-Feb;32(1):47-86. PubMed PMID: 20383346. 3. Borelli C, Schaller M, Niewerth M, Nocker K, Baasner B, Berg D, Tiemann R, Tietjen K, Fugmann B, Lang-Fugmann S, Korting HC. Modes of action of the new arylguanidine abafungin beyond interference with ergosterol biosynthesis and in vitro activity against medically important fungi. Chemotherapy. 2008;54(4):245-59. doi: 10.1159/000142334. Epub 2008 Jun 30. PubMed PMID: 18587237. |