| Description | AalphaC (2-Amino-alpha-carboline) is a potential carcinogen. |
| Synonyms | 2-Amino-alpha-carboline, Aalpha C, 2-氨基-9H-吡啶[2,3-b]吲哚, Aalpha-C |
| molecular weight | 183.21 |
| Molecular formula | C11H9N3 |
| CAS | 26148-68-5 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 60 mg/ml (327.49 mM) |
| References | 1. Yuan ZX, Jha G, McGregor MA, King RS. Metabolites of the carcinogen 2-amino-alpha-carboline formed in male Sprague-Dawley rats in vivo and in rat hepatocyte and human HepG2 cell incubates. Chem Res Toxicol. 2007 Mar;20(3):497-503. Epub 2007 Feb 10. PubMed PMID: 17291013; PubMed Central PMCID: PMC2105743. 2. Smith CJ, Qian X, Zha Q, Moldoveanu SC. Analysis of alpha- and beta-carbolines in mainstream smoke of reference cigarettes by gas chromatography-mass spectrometry. J Chromatogr A. 2004 Aug 13;1046(1-2):211-6. PubMed PMID: 15387190. 3. Novak M, Nguyen TM. Unusual reactions of the model carcinogen N-acetoxy-N-acetyl-2-amino-alpha-carboline. J Org Chem. 2003 Dec 26;68(26):9875-81. PubMed PMID: 14682678. 4. Horie H, Zeisig M, Hirayama K, Midtvedt T, Möller L, Rafter J. Probiotic mixture decreases DNA adduct formation in colonic epithelium induced by the food mutagen 2-amino-9H-pyrido[2,3-b]indole in a human-flora associated mouse model. Eur J Cancer Prev. 2003 Apr;12(2):101-7. PubMed PMID: 12671533. |