Description | A2793 is a dual inhibitor of TWIK-associated acid-sensitive K+ channel 1 (TASK-1)/TRESK, with an IC50 for mTRESK of 6.8 μM. It is more selective for TRESK, and relatively weaker for TREK-1 and TALK-1. |
Target activity | TRESK (mouse):6.8 μM (IC50) |
Synonyms | 2-[(5-氯-8-喹啉基)氧基]乙酸乙酯 |
molecular weight | 265.69 |
Molecular formula | C13H12ClNO3 |
CAS | 88349-90-0 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
Solubility | DMSO: 22.5 mg/mL (84.69 mM) |