| Description | 8-Azaadenine (NSC-32797) is an inhibitor of xanthine oxidase with IC50 of 0.54 μM and Ki of 0.66 μM. |
| Synonyms | NSC 32797, NSC32797, NSC-32797 |
| molecular weight | 136.11 |
| Molecular formula | C4H4N6 |
| CAS | 1123-54-2 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 10 mg/mL (73.46 mM) |
| References | 1. Minton JA, et al. Heterologous complementation studies reveal the solute transport profiles of a two-member nucleobase cation symporter 1 (NCS1) family in Physcomitrella patens. Plant Physiol Biochem. 2016 Mar;100:12-17. 2. Stachelska-Wierzchowska A, et al. Site-Selective Ribosylation of Fluorescent Nucleobase Analogs Using Purine-Nucleoside Phosphorylase as a Catalyst: Effects of Point Mutations. Molecules. 2015 Dec 28;21(1):E44. 3. Chawla M, et al. Structural and Energetic Impact of Non-Natural 7-Deaza-8-Azaadenine and Its 7-Substituted Derivatives on H-Bonding Potential with Uracil in RNA Molecules. J Phys Chem B. 2015 Oct 15;119(41):12982-9. 4. Sheu SY, Lin YC, Chiang HC. Inhibition of xanthine oxidase by synthetic cytokinin analogues. Anticancer Res. 1997 Mar-Apr;17(2A):1043-9. |