| Description | 7-Methyladenine (NSC-7857) can be used as a marker of exposure to exogenous and carcinogenic methylating agents. |
| Synonyms | NSC7857, 7-甲基腺嘌呤, NSC-7857, NSC 7857 |
| molecular weight | 149.15 |
| Molecular formula | C6H7N5 |
| CAS | 935-69-3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 1.49 mg/mL (9.99 mM), Sonication is recommended. |
| References | 1. Harroun SG, et al. Biomarkers of cigarette smoking and DNA methylating agents: Raman, SERS and DFT study of 3-methyladenine and 7-methyladenine. Spectrochim Acta A Mol Biomol Spectrosc. 2017 Apr 5;176:1-7. 2. Michelson AZ, et al. Gas-phase studies of purine 3-methyladenine DNA glycosylase II (AlkA) substrates. J Am Chem Soc. 2012 Jun 13;134(23):9622-33. 3. Tokuda S, et al. Effect of the uncharged imidazolium moiety in adenine on endothelium-independent relaxation in the contracted thoracic aorta of Sprague-Dawley rats. Biosci Biotechnol Biochem. 2012;76(4):828-30. Epub 2012 Apr 7. 4. von Kügelgen I, et al. Cloning and functional expression of a novel Gi protein-coupled receptor for adenine from mouse brain. Mol Pharmacol. 2008 Feb;73(2):469-77. Epub 2007 Nov 1. |