| Description | 653-47 acts as a potentiator significantly enhancing the inhibitory activity of 666-15 on the cAMP-response element binding protein (CREB), while it also exhibits mild CREB inhibitory properties itself, with an IC50 value of 26.3 μM [1]. |
| In vitro | 653-47 (5-10 μM) synergistically inhibits gene transcription mediated by CREB with 666-15 [1]. |
| molecular weight | 370.83 |
| Molecular formula | C20H19ClN2O3 |
| CAS | 1224678-75-4 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |