| Description | 6-Aminochrysene (6-Chrysenamine) is an inhibitor of the growth of several solid experimental tumors and can be used in studies about splenomegaly, breast cancer and myeloid leukemia. |
| In vivo | 6-Aminochrysene 在大鼠肝微粒体中抑制了苯胺的羟基化、对硝基苯甲醚的O-去甲基作用以及氨基比林的N-去甲基作用[1]。 |
| Animal experiments | In Male CD rats, intraperitoneal injections of 6-Aminochrysene with 25, 50, and 100 mg/kg are pre-treated once daily for 3 consecutive days before sacrifice[1]. |
| Synonyms | 6-Chrysenamine |
| molecular weight | 243.3 |
| Molecular formula | C18H13N |
| CAS | 2642-98-0 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 90.0 mg/mL (369.9 mM), Sonication is recommended. |
| References | 1. Russo R, et al. Effects of 6-aminochrysene on liver microsomal enzyme activity. Xenobiotica. 1976 Apr;6(4):201-5. 2. Lambelin G, et al. Carcinogenicity of 6-aminochrysene in mice. Eur J Cancer. 1975 May;11(5):327-34. |