Description | 6-Amino-8-trifluoromethylphenanthridine (6A-8tFP) is an antiprion agent and a derivative of 6-aminophenanthridine . It inhibits protein folding activity of the ribosome (PFAR) when used at a concentration of 150 μM. 6A-8tFP directly competes with protein substrates for the ribosomal active site. |
molecular weight | 262.23 |
Molecular formula | C14H9F3N2 |
CAS | 651055-83-3 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
Solubility | Ethanol: Soluble DMSO: Soluble |