Description | 5-(2-Furyl)-2-hydroxybenzoic acid is an inhibitor of glycolate oxidase (GO) and can be used to study metabolism-related disorders such as primary hyperoxaluria type 1 (PH1). |
In vitro | LDH-IN-2L (10 μM; 24 h) 在 Agxt1-/- 小鼠原代肝细胞中抑制草酸产生的抑制率为 89%[1]. |
Synonyms | LDH-IN-2 |
molecular weight | 204.18 |
Molecular formula | C11H8O4 |
CAS | 893739-96-3 |
Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
References | 1. Moya-Garzón MD, et al. Salicylic Acid Derivatives Inhibit Oxalate Production in Mouse Hepatocytes with Primary Hyperoxaluria Type J Med Chem. 2018 Aug 23;61(16):7144-7167. |