| Description | 4-METHOXYCHALCONE (2-(4-Methoxybenzal)Acetophenone) is a natural compound that enhanced adipocyte differentiation, |
| In vivo | 4-MC促进了脂质积累，并在脂肪细胞分化过程中强烈上调了脂肪生成标志物的表达，包括PPARγ、aP2、FAS和脂联素[1]。 |
| Synonyms | 2-(4-Methoxybenzal)Acetophenone, 4-甲氧基查耳酮 |
| molecular weight | 238.28 |
| Molecular formula | C16H14O2 |
| CAS | 959-33-1 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 22.5 mg/mL (94.42 mM) |
| References | 1. Younho, Han, Sung, et al. Regulatory effects of 4-methoxychalcone on adipocyte differentiation through PPARγ activation and reverse effect on TNF-α in 3T3-L1 cells[J]. Food & Chemical Toxicology, 2017. 2. Lim J , Lee S H , Cho S , et al. 4-methoxychalcone enhances cisplatin-induced oxidative stress and cytotoxicity by inhibiting the Nrf2/ARE-mediated defense mechanism in A549 lung cancer cells[J]. Molecules and Cells, 2013, 36(4):340-346. |